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The 10-place shortlist
- Barichara, Colombia — sandstone streets, mountain views, and a slower small-town pace.
- Cuenca, Ecuador — colonial architecture, markets, museums, and a mild Andean setting.
- Sucre, Bolivia — whitewashed historic streets and a comfortable base for cultural day trips.
- Salta, Argentina — plazas, high-desert landscapes, wineries, and scenic road routes.
- Colonia del Sacramento, Uruguay — a compact riverfront old town easily paired with Montevideo or Buenos Aires.
- Paraty, Brazil — preserved streets, Atlantic Forest excursions, and island-dotted water.
- Arequipa, Peru — volcanic-stone architecture and access to the wider Colca region.
- Pucón, Chile — a lake-and-volcano base for active travel with conditions checked carefully.
- El Chaltén, Argentina — a small Patagonian hiking base where weather dictates the plan.
- Olinda, Brazil — colourful hills, historic churches, and a strong arts identity near Recife.
How to choose the right one
Build around altitude, season, and transfer time rather than pinning distant places into one rushed route. A single region with two or three bases is usually stronger than a continent-spanning checklist.
Compare the bookable pieces
Use comparison tools to map realistic routes and prices, then verify the final terms with the airline, accommodation, or activity operator before paying.
Compare flight routes on AviasalesCompare dates, routes, sellers, baggage, and total fare conditionsCompare ↗Compare flexible routes on Kiwi.comVerify carriers, connections, and itinerary protections before purchaseCompare ↗Browse destination activities on KlookCheck current availability, reviews, cancellation terms, and operator detailsCompare ↗
Before you book
- Confirm current entry, health, safety, weather, and transport information with official sources.
- Compare the complete trip cost, including transfers, baggage, local transport, and cancellation terms.
- Do not treat ‘hidden gem’ as ‘empty’: respect residents, local rules, protected areas, and capacity limits.
- Avoid geotagging fragile or restricted natural sites when local guidance discourages it.
Editorial note: Independently researched by Tara C. Last reviewed August 5, 2026. Always verify current airline, airport, destination, health, safety, and entry rules with the relevant official source.